Designation:
Research Scientist, School of Biosciences
Qualifications:
PhD, The University of Transdisciplinary Health sciences and Technology, (TDU), Bangalore
Area of Specialization:
Ayurveda formulations/extracts, Metabolic disorders, Oncology signalling networks, System biology.
Anjana T. earned her Ph.D. from The University of Trans-Disciplinary Health Sciences and Technology (TDU), Bangalore, where she investigated the mechanisms of action of classical Ayurvedic polyherbal formulations in the management of type 2 diabetes and obesity. Her work employed multi-modal approaches to explore their multi-targeted therapeutic effects. Anjana has also worked in companies such as Cellworks Inc. and Metflux Research Pvt. Ltd., where she contributed to the development of systems biology–driven pipelines aimed at applications in precision oncology, dermatology, and metabolic disorders. She is interested in integrative approaches that bridge Ayurveda and modern biology, with a focus on exploring the translational potential of Ayurvedic practices in managing metabolic disorders.
Publications:
- Thottapillil, A., Kouser, S., Kukkupuni, S. K., & Vishnuprasad, C. N. (2021). An ‘Ayurveda-Biology’platform for integrative diabetes management. Journal of ethnopharmacology, 268, 113575. https://doi.org/10.1016/j.jep.2020.113575
- Kalankariyan, S., Thottapillil, A., Saxena, A. et al. An in silico approach deciphering the commensal dynamics in the cutaneous milieu. npj Syst Biol Appl 11, 42 (2025). https://doi.org/10.1038/s41540-025-00524-y
- Thottappillil A, Sahoo S, Chakraborty A, Kouser S, Ravi V, Garawadmath S, Banvi P, Kukkupuni SK, Mohan SS, Vishnuprasad CN. In vitro and in silico analysis proving DPP4 inhibition and diabetes-associated gene network modulation by a polyherbal formulation: Nisakathakadi Kashaya. J Biomol Struct Dyn. 2024;42(24):13588-13602. https://doi.org/10.1080/07391102.2023.2276880
- UCA Jaleel, Vishnuprasad Chethala N, Sathish S, Anjana Thottapillil, Jinu Raj K R, Subrahmanya Kumar Kukkupuni, Prasanna Kulkarni, Rakhila M, Ayisha Safeeda, Andrew Titus Manuel, Sandesh EPA. Artificial Neural Network Based Self Organizing Maps Analysis for Clinical Trials of Indian Systems of Medicine. https://ssrn.com/abstract=4468365 or http://dx.doi.org/10.2139/ssrn.4468365.
- AnjanaThottappillil, Sania Kouser, Abhi V. Badiger, Priyanka Gladys Pinto, Srimathy Ramachandran, Suresh Janadri, Manjunatha P Mudagal, Subrahmanya Kumar Kukkupuni, Suma Mohan S. Anti-diabetic and anti-adipogenic effects of polyherbal formulation Varanadi kashayam with a focus on incretin modulation. doi: https://doi.org/10.1101/2024.06.29.601306
- Prasad CN, Anjana T, Banerji A, Gopalakrishnapillai A. Gallic acid induces GLUT4 translocation and glucose uptake activity in 3T3-L1 cells. FEBS Lett. 2010 Feb 5;584(3):531-6. doi: 10.1016/j.febslet.2009.11.092
- Madeleine Turcotte, Raphael Charles Bosse, Kimberly E. Hawkins, Amy Meacham, Vindhya Vijay, Girish Chinnaswamy, Manju Sengar, Ansu Kumar, Shwetha K, Anisha Kamath, AnjanaT.Nair, Karthik S. Raju, Taher Abbasi, Shireen Vali, Christopher R. Cogle and Leylah M. Drusbosky. Personalized therapy design for Early T-Cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) using computational biology modeling with in vitro validation. Blood 2017 (Abstracts) 130:1448.