Dr. Shilpee Jain

Shilpee Jain is deeply involved in biomedical research and entrepreneurship. Her expertise spans hyperthermia, cancer therapeutics, medical microrobots, translational research, tissue engineering, and magnetic/carbon nanomaterials.

She also worked as an INSPIRE Faculty Fellow at the Center for Biosystems Science and Engineering, Indian Institute of Science, for five years and developed innovative biomedical devices. She co-founded MagHeals Private Limited, translating her research outcomes for clinical applications.

She has secured significant research grants, including the BIG BIRAC grant and the INSPIRE Faculty Award, recognising her contributions to the field.

Shilpee Jain’s research output is also evident through her publications in reputable international journals, such as Biomaterials, Carbon, Nanoscale, and Hyperthermia. 

Research Interest

We are a team of bioengineers developing micro/nanodevices for various biomedical applications. The major focus of our work currently is the efficient intracellular delivery of biomolecules using external stimulations for better therapeutic outcomes. We are also interested in developing smart degradable bandages for wound healing, which can support the regenerated tissue and enhance rate of recovery by providing external electrical stimulation.

Publications 

Corresponding Author 

1. Magneto-conducting multifunctional Janus microbots for intracellular delivery of biomolecules. Sachin Latiyan, Kaushik Suneet and Shilpee Jain*. Journal of Tissue Engineering and Regenerative Medicine (IF 3.9, citations 2) 2021. 15, p. 625-633. 
2. Magnetic nanofibers based bandage for skin cancer treatment: a non-invasive hyperthermia therapy. Kaushik Suneet, Tamasa De, Annapoorni Rangarajan and Shilpee Jain*. Cancer Reports (IF 1.7, citations 24) 2020. 3, e1281. 
3. Magnetic hyperthermia adjunctive therapy for fungi: in vitro studies against Candida albicans. Kaushik Suneet, Shreyas Sridhar, Purvi Agiwal, Mittanamalli S Sridhar, Kaustuv Sanyal and Shilpee Jain*; International Journal of Hyperthermia (IF 3.9, citations 6) 2019. 36, p. 545-553. 
4. Chitosan−Glycerol Gel as Barrier Formulation for Metal Allergy. Venkata Subramanian Ramesan and Shilpee Jain*; ACS Omega (IF 3.5, citations 6) 2019. 4, p. 5900-5903. 
5. The combined effect of thermal and chemotherapy on HeLa cells using a magnetically actuated smart textured fibrous system. Pranav Tiwari, Sakshi Agarwal, Sachchidanand Srivastava and Shilpee Jain*; Journal of Biomedical Materials Research, Part B Applied Biomaterials (IF 3.3, citations 15) 2018. 106, p. 40-51. 
6. Study of smart antibacterial PCL-xFe3O4 thin films using mouse NIH-3T3 fibroblast cells in vitro. Ganesh Pai, Ajay V Kulkarni and Shilpee Jain*; Journal of Biomedical Materials Research, Part B Applied Biomaterials (IF 3.3, citations 9) 2017. 105, p. 795–804. 

Co-author 

7. Synthesis of Graphene oxide-Fe3O4 based nanocomposites using the mechanochemical method and in vitro magnetic hyperthermia. Aleksandr S. Kamzin, Bashar Issa, Venkatesha Narayanaswamy, Shilpee Jain, Sachin Latiyan, Chandan Srivastava, Hemant Kumar and Ihab M. Obaidat; International Journal of Molecular Sciences (IF 4.1, citations 44) 2019. 20, p.3368-3380. 
8. Remarkably selective biocompatible turn-on fluorescent probe for detection of Fe3+ in human blood samples and cells. Vishaka V H, Manav Saxena, Geetha Balakrishna R, Sachin Latiyan, Shilpee Jain; RSC Advances (IF 3.3, citations 20) 2019. 9, p. 27439-27448. 
9. A composite of hyaluronic acid modified graphene oxide and iron oxide nanoparticles for targeted drug delivery and magneto-thermal therapy. Nilkamal Pramanik, Santha Laxmi, Sunaina Rao, Kaushik Suneet, Shilpee Jain, Annapoorni Rangarajan and Siddharth Jhunjhunwala; ACS Omega (IF 3.5, citations 52) 2019. 4, p. 9284−9293. 
10. The Role of interface quality in iron oxide core/shell nanoparticles on heating efficiency and transverse relaxivity. Venkatesha Narayanaswamy, Ihab M Obaidat, Sachin Latiyan, Shilpee Jain, Chiranjib Nayek, Sumana Goankar, M-Ali AL-Akhras, and Imaddin A. Al-Omari; Materials Express (IF 1.5, citations 9) 2019. 9, p. 328-336.
11. Single coating of zinc ferrite renders magnetic nanomotors therapeutic and stable against agglomeration. Pooyath Lekshmy Venugopalan, Shilpee Jain, Srinivasrao Shivashankar and Ambarish Ghosh; Nanoscale (IF 7.7, citations 38) 2018. 10, p. 2327-2332. 
12. Vertical electric field induced bacterial growth inactivation on amorphous carbon electrodes. Shilpee Jain, Ashutosh Sharma and Bikramjit Basu; Carbon (IF 9.5, citations 20) 2015. 81, p. 193-202. 
13. Vertical electric field stimulated neural cell functionality on porous amorphous carbon electrodes. Shilpee Jain, Ashutosh Sharma and Bikramjit Basu; Biomaterials (IF 10.3, citations 59) 2013. 34, p. 9252-9263. 
14. Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates. Shilpee Jain, Thomas J Webster, Ashutosh Sharma and Bikramjit Basu; Biomaterials (IF 10.3, citations 46) 2013. 34, p. 4891-4901. 
15. Patterned growth and differentiation of neural cells on polymer-derived carbon substrates with micro/nanostructures in vitro. Jaba Mitra,* Shilpee Jain,* Ashutosh Sharma and Bikramjit Basu; Carbon (IF 9.5, citations 54) 2013. 65, p. 140-155. (*Equal contribution) 
16. In vitro cytocompatibility assessment of amorphous carbon structures using neuroblastoma and Schwann cells. Shilpee Jain, Ashutosh Sharma and Bikramjit Basu; Journal of. Biomedical Materials Research Part B (IF 3.3, citations 41) 2013. 101B, p. 530-531. 

Book Chapters

17. Functionalized magnetic nanoparticles for treating bone diseases. Shilpee Jain, Neelima Mahato and Alok Kumar. Nanomedicine – second edition, Edited by Dr. Thomas Webster, Woodhead Publishing Series in Biomaterials, 2023, p59-79. 
18. Magnetic properties of 2-D Materials, Rajesh Katoch and Shilpee Jain, CRC Press;, 2022, p 95-122.