Chanakya Premier League – Season 1: A Grand Celebration of Cricketing Spirit

April 24, 2025

The inaugural edition of the Chanakya Premier League (CPL) – Season 1 proved to be a remarkable success, marked by exhilarating matches, extraordinary performances, and unwavering sportsmanship. The tournament commenced with great enthusiasm on 10th April 2025, and culminated in a thrilling grand finale on 24th April 2025. The league featured four dynamic and spirited

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Raita Siri – Farmers Empowerment Programme at Chanakya University

April 24, 2025

Chanakya University hosted the Raita Siri – Farmers Empowerment programme, reaffirming its commitment to rural empowerment, sustainable agriculture, and grassroots innovation. The event was held on 24th April 2025 at the University Campus and witnessed the presence of several distinguished guests from diverse domains, including agriculture, science, governance, and academia. The programme was jointly organized

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Prof. Yashavantha Dongre

An academician par excellence, Prof. Dongre has over 28 years of research experience and has completed his post-doctoral degree at Ritsumeikan University, Japan & Graduate University of Advanced Studies, Osaka, Japan. 

Prof. Dongre has served as the Professor of Commerce and the Director of Planning, Monitoring and Evaluation Board at the University of Mysore. He is also a Consultant to the High-Powered Committee on Cooperatives set up by the Ministry of Agriculture, Government of India and serves as the Co-Secretary of the ICA-AP Committee on Cooperatives in Educational Institutions. 

Prof. Yashavantha Dongre has held various responsible positions including Vice-Chancellor (I/C), Registrar, Director of the Post Graduate Centre and Director of Planning. He has published over 100 journal articles and 8 edited books. He is the Founder Member of The Third Sector Research Group, India (TSRGI), founded in 1993. This network of researchers, which began as an informal entity with three researchers from one university, has today expanded into a major research group in India with 80 members from five southern States of India. He has designed the Masters’ program in nonprofit management at the University of Mysore, titled Master of Management of Non-Profit Organisations (MMNPO) and run by the Vivekananda Institute of Leadership Development. 
 

Prof Dongre has been undertaking research projects with various agencies such as Manipal University, Asia Pacific Philanthropy Consortium, University of Technology Sydney, Australia, etc. He has been serving on the Editorial Boards of two Journals in Kannada – Arivu Baraha (Knowledge and Expression) an independent social science journal and Abhivruddhi Adhyayana (Development Studies) brought out by the Kannada University.   He currently chairs the Asia Pacific Regional Research Committee of the International Cooperative Alliance.

Chanakya Samvad – A Panel Discussion on The World Order in Flux

April 16, 2025

Date: 16th April 2025Venue: Yuva Patha, Jayanagar, BengaluruOrganized by: School of Arts, Humanities and Social Sciences, Chanakya University The School of Arts, Humanities and Social Sciences at Chanakya University successfully hosted a compelling edition of Chanakya Samvad, a flagship intellectual forum for dialogue and debate. The theme of this edition, “The World Order in Flux”,

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Samagam: Faculty and Staff meet to celebrate

April 3, 2025

At Chanakya University, the spirit of togetherness and collaboration came alive during Samagam, the much-anticipated Faculty and Staff Meeting. Held at the Preksha Auditorium on 03rd April 2025, the gathering was a heartfelt celebration of community, progress, and a shared vision for the future. Prof. Yashavantha Dongre, Vice-Chancellor of Chanakya University, formally welcomed the gathering.

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Report on Special Talk by Sri Abhishek Sharma: “Upskill with AI for Career Growth”

March 13, 2025

Sri Abhishek Sharma – Founder, The Upskill School and a seasoned technology consultant and AI thought leader, delivered an enlightening talk titled “Upskill with AI for Career Growth” at the Bengaluru Tech Forum. The session attracted professionals from diverse sectors, all keen to understand the transformative impact of artificial intelligence on career trajectories.​Mr. Sharma began

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Report on Vanitha Vandana – Women’s Day Celebration at Chanakya University

March 8, 2025

On March 8, 2025, Chanakya University celebrated International Women’s Day with a vibrant event titled Vanitha Vandana, honoring the resilience and achievements of women across diverse sectors. The celebration aimed to spotlight the contributions of women from various walks of life, emphasizing inclusivity and empowerment.​ The celebration fostered a sense of unity and inspiration among

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A Critical Scholarly Dialogue on the Geography, Chronology, and Ethnic Identity of the Rigvedic Aryans and their Place within the Broader Indian Civilisation 

March 8, 2025

School of Arts, Humanities and Social Sciences a session featured Dr Koenraad Elst, Shri Shrikant Talageri (online), and Shri Jijith Nadumuri Ravi as panellists. Dr Elst is an Oriental philologist and historian, who has authored more than 30 books on the Aryan debate, the Ayodhya movement and many other political and religious issues. Talageri is

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Report on Special Talk by Dr. K. K. Agnihotri: “Contemporary Geopolitical Developments in the Indian Ocean Region and Impact on India’s Maritime Security”

March 8, 2025

Dr. K. K. Agnihotri, a distinguished Research Fellow at the National Maritime Foundation, delivered an insightful lecture on the evolving geopolitical landscape of the Indian Ocean Region (IOR) and its implications for India’s maritime security. The session, held at the Naval War College in Goa, attracted defense strategists, naval officers, and scholars.​ Dr. Agnihotri commenced

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Report on Chanakya Creative Collection Exhibition

March 6, 2025

Chanakya University hosted the Chanakya Creative Collection exhibition, a vibrant showcase of artistic ingenuity and entrepreneurial spirit. Held at the university’s Knowledge Centre, the event featured an array of handcrafted items created by students and staff, reflecting the institution’s commitment to fostering creativity and community engagement.​ The exhibition offered a platform for participants to buy

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Talk by Prof. HS Subramanya at the 17th Young Investigator’s meeting

March 5, 2025

Prof. HS Subramanya, Pro Vice-Chancellor, Professor & Dean, School of Biosciences gave a talk on ‘Chanakya University, School of Biosciences and Career opportunities’ at the 17th Young Investigator’s meeting 2025 (YIM 2025) organized by IndiaBioscience at Agra, Uttar Pradesh held from 3rd to 5th March, 2025.

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Prof. H.S. Subramanya

Prof H.S. Subramanya is a distinguished scientist with a strong academic background and extensive experience in research and industry spanning across three decades. He is a renowned expert in Structural biology and Drug research. 

He obtained his doctoral degree (PhD) from Indian Institute of Science, Bengaluru, India and his thesis was on ‘Structure of Sesbania Mosaic Virus at 4.7A^o resolution”. He completed his Post-doc at Oxford University, UK where he has extensively worked on the biochemical and structural aspects of enzymes belonging to the DNA replication pathway. 

He has also served as Assistant Director at Central drug research institute (CDRI), Lucknow, India. He has over 20 years of experience in drug discovery platform at Aurigene Discovery Technologies Ltd., Bengaluru, India where he served in multiple capacities as director, Vice president and Senior Vice President. He has also served as the Director of Institute of Bioinformatics and Applied Biotechnology (IBAB). He has over 50 peer-reviewed publications and 19 patents to his credit. 

Publications 

1. Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family Aishwarya H. Arole, Prashant Deshmukh, Ashok Sridhar, Shruti Mathur, Mahesh Mahalingaswamy, Hosahalli Subramanya, Nandakumar Dalavaikodihalli Nanjaiah and Balasundaram Padmanabhan Acta Cryst. (2023). D79, 758–774.
2. Profilin is involved in G1 to S phase progression and mitotic spindle  orientation during Leishmania donovani cell division cycle Ambaru B, Gangadharan G M, Subramanya H S, Gupta CM PLOS ONE, 17(3), 2022

3. Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action. Ramulu Poddutoori, Kimberly Aardalen, Kiran Aithal, Sanjeev Surendranath Barahagar, Charamanna Belliappa, Mark Bock, Shekar Chelur, Andrea Gerken, Sreevalsam Gopinath, Bjoern Gruenenfelder, Michael Kiffe, Maithreyi Krishnaswami, John Langowski, Sudharshan Madapa, Kishore Narayanan, Chetan Pandit, Sunil Kumar Panigrahi, Mark Perrone, Ravi Kumar Potakamuri, Murali Ramachandra, Anuradha Ramanathan, Rita Ramos, Emine Sager, Susanta Samajdar, Hosahalli S Subramanya, Devaraja Seethappa Thimmasandra, Eleni Venetsanakos, Henrik Möbitz Journal of Medicinal Chemistry 65 (5), 4350-4366 (2022)

4. Draft genome sequence of the community-associated staphylococcus aureus sequence type 88 strain LVP-7, isolated from an ocular infection Savitha Nadig, Sneha Murthy, Muralidharan Vandanashree, Hosahalli S Subramanya, Balasubramanian Gopal, Shruthi Vembar Microbiology Resource Announcements 10 (7), e00077-21 (2021)
5. Whole Genome Sequences of Aedes aegypti (Linn.) Field Isolates from Southern India. Bernard, V, Moudgalya, S, Reegan, D, Sreekanthreddy, P, Mohan, A, Subramanya, H S, Vembar, S S, Ghosh, S. BioRxiv. (2020)
6. Actin sequestering protein, profilin, regulates intracellular vesicle transport in Leishmania Ambaru B, Gopalsamy A, Tammana TVS, Subramanya HS, Gupta CM Molecular & Biochemical Parasitology 238, 111280 (2020)

7. Network pharmacology study of Curcuma longa L.: potential target proteins and their functional enrichment analysis S Kumari, HS Subramanya BMC Research Notes 13 (1), 1-5 (2020)

8. Selective vulnerability to pyrimidine starvation in hematologic malignancies revealed by AG-636, a novel clinical-stage inhibitor of dihydroorotate dehydrogenase Gabrielle McDonald, Victor Chubukov, John Coco, Kevin Truskowski, Rohini Narayanaswamy, Sung Choe, Mya Steadman, Erin Artin, Anil K Padyana, Lei Jin, Sebastien Ronseaux, Charles Locuson, Zi-Peng Fan, Tabea Erdmann, Alan Mann, Sebastian Hayes, Mark Fletcher, Kavitha Nellore, Siva Sanjeeva Rao, Hosahalli Subramanya, K Satish Reddy, Sunil K Panigrahi, Thomas Antony, Sreevalsam Gopinath, Zhihua Sui, Nelamangala Nagaraja, Lenny Dang, Georg Lenz, Jonathan Hurov, Scott A Biller, Josh Murtie, Kevin M Marks, Danielle B Ulanet Molecular Cancer Therapeutics 19 (12), 2502-2515 (2020)

9. Discovery of CA-4948, an orally bioavailable IRAK4 inhibitor for treatment of hematologic malignancies Venkateshwar Rao Gummadi, Anima Boruah, Bharathi Raja Ainan, Brahma Reddy Vare, Srinivas Manda, Hari Prakash Gondle, Shiva Nagendra Kumar, Subhendu Mukherjee, Suraj T Gore, Narasimha Rao Krishnamurthy, Sivapriya Marappan, Shilpa S Nayak, Kavitha Nellore, Wesley Roy Balasubramanian, Archana Bhumireddy, Sanjeev Giri, Sreevalsam Gopinath, Dodheri S Samiulla, Girish Daginakatte, Aravind Basavaraju, Shekar Chelur, Rajesh Eswarappa, Charamanna Belliappa, Hosahalli S Subramanya, Robert N Booher, Murali Ramachandra, Susanta Samajdar ACS medicinal chemistry letters 11 (12), 2374-2381 (2020)

10. India Needs More Policy Research HS Subramanya, G Saberwal Current Science 116 (8), 1279-1280 (2019)

11. Some data quality issues at Clinical Trials. Gov Chaturvedi, N., Mehrotra, B., Kumari, S. Gupta, S Subramanya HS, & Saberwal G Trials 20, 378 (2019)
12. Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells A.K. Mohamad Fairus, B. Choudhary, S. Hosahalli, N. Kavitha, O. Shatrah Biochimie, 135:154-163 (2017)

13. Dihydroorotate dehydrogenase inhibitors target c-Myc and arrest melanoma, myeloma and lymphoma cells at S-phase MS Dorasamy, B Choudhary, K Nellore, H Subramanya, PF Wong Journal of Cancer 8 (15), 3086 – 3098 (2017)

14. Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH. Iskandar Abdullah, Chin Fei Chee, Yean-Kee Lee, Siva Sanjeeva Rao Thunuguntla, K Satish Reddy, Kavitha Nellore,Thomas Antony, Jitender Verma, Kong Wai Mun, Shatrah Othman, Hosahalli Subramanya, Noorsaadah Abd Rahman Bioorg Med Chem, 2015 Aug 5;23 (15): 4669-80.

15. AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei—Crystal structure, mode of action, and biological activity Narasimha Rao, K., Lakshminarasimhan, A., Joseph, S., Lekshmi, S. U., Lau, M.- S., Takhi, M., Sreenivas, K., Nathan, S., Yusof, R., Abd. Rahman, N., Ramachandra, M., Antony, T. and Subramanya, H. Protein Science, 2015, 24, 832–840.

16. Discovery of O-(3-carbamimidoylphenyl)-l-serine amides as matriptase inhibitors using a fragment-linking approach. Rajeev Goswami, Gerd Wohlfahrt, Subhendu Mukherjee, Chakshusmathi Ghadiyaram, Jwala Nagaraj, Leena K Satyam,Krishnaprasad Subbarao, Sreevalsam Gopinath, Narasimha R Krishnamurthy, Hosahalli S Subramanya, Murali Ramachandra Bioorg. Med. Chem. Lett. 2015 Feb 17, 25(3), 616-20

17. X-ray structure of PTP1B in complex with a new PTP1B inhibitor. M V V V Sekhar Reddy, Chakshumathi Ghadiyaram, Sunil Kumar Panigrahi, Narasimha Rao Krishnamurthy, Subramanya Hosahalli, Arun P Chandrasekharappa, Deepankar Manna, Sangamesh E Badiger, Pramod K Dubey, Lakshmi Narasu Mangamoori Protein Pept Lett., 2014 ;21(1):90-3

18. Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitor. Mohamed Takhi, Kandepu Sreenivas, Chandrashekar K. Reddy, Mahadari Munikumar, Kolakota Praveena, Pabolu Sudheer, Bandaru N.V.M. Rao, Gollamudi Ramakanth, Jampala Sivaranjani, Shardaprasad Mulik, Yeruva R. Reddy, Krishnamurthy Narasimha Rao, Rentala Pallavi, Anirudha Lakshminarasimhan, Sunil K. Panigrahi, Thomas Antony, Iskandar Abdullah, Yean K. Lee, Murali Ramachandra, Rohana Yusof, Noorsaadah A. Rahman, Hosahalli Subramanya European Journal of Medicinal Chemistry, Volume 84, 12 September 2014, Pages 382-394.

19. A facile synthesis of 7,12-dihydro-1,3,6,7,12-pentaazapleiadenes by domino reaction Vishnu Basetti, Rangarao Pallepati, Emima Thadi, Subramanya Hosahalli and Vijay Potluri Heterocycl. Commun. 2014; 20(4): 207–214

20. Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy. Rajeev Goswami, Subhendu Mukherjee, Chakshusmathi Ghadiyaram, Gerd Wohlfahrt, Ramesh K Sistla, Jwala Nagaraj, Leena K Satyam, Krishnaprasad Subbarao, Rajendra K Palakurthy, Sreevalsam Gopinath, Narasimha R Krishnamurthy, Tarja Ikonen, Anu Moilanen, Hosahalli S Subramanya, Pekka Kallio, Murali Ramachandra Bioorg Med Chem 2014 Jun 18;22(12):3187-203.

21. Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors Rajeev Goswami, Subhendu Mukherjee, Gerd Wohlfahrt, Chakshusmathi Ghadiyaram, Jwala Nagaraj, Beeram Ravi Chandra, Ramesh K. Sistla, Leena K Satyam, Dodheri S. Samiulla, Anu Moilanen, Hosahalli S. Subramanya, and Murali Ramachandra ACS Med. Chem. Lett., 2013, 4 (12), pp 1152–1157

22. Diphenylether derivative as selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) over t-cell protein tyrosine phosphatase (TCPTP) identified through virtual screening. Reddy MV1, Ghadiyaram C, Panigrahi SK, Hosahalli S, Mangamoori LN Mini Rev Med Chem. 2013 Oct; 13 (11):1602-6

23. Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode Venkateshwar Rao Gummadi, Sujatha Rajagopalan, Looi Chung Yeng, Mohammadjavad Paydar, Girish Aggunda Renukappa, Bharathi Raja Ainan, Narasimha Rao Krishnamurthy, Sunil Kumar Panigrahi, Kumari Mahasweta, Sangeeth Raghuramachandran, Manoj Rajappa, Anuradha Ramanathan, Anirudha Lakshminarasimhan, Murali Ramachandra, Wong Pooi Fong, Mohammad Rais Mustafa, Srinivas Nanduri, Subramanya Hosahalli Bioorganic & Medicinal Chemistry Letters, Volume 23, Issue 17, 1 September 2013, Pages 4911–4918
24. A facile synthesis of tetracyclic benzo-pyridonaphthyridines by domino reaction Vishnu Basetti, Rangarao Pallepati, Subramanya Hosahalli and Vijay Potluri Tetrahedron Letters, Volume 54, Issue 15, 10 April 2013, Pages 2014-2017

25. A structure-based strategy for new drug discovery. Ramesh S, Chakshusmathi G, Nagaraja CS and Subramanya, H.S. (2006)IPT 20, 18.

26. Role of Lys-226 in the Catalytic Mechanism of Bacillus stearothermophilus Serine Hydroxymethyltransferase – Crystal Structure and Kinetic Studies. Bhavani S, Trivedi V, Ambili M, Jala VR, Subramanya, H.S, Purnima, K, Prakash, V, Appaji Rao, N, Savithri, H. S. (2005)Biochemistry, 44, 6929-37.

27. Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase.Varshney U, Ramesh V, Madabushi A, Gaur R, Subramanya, H.S. and RajBhandary UL (2004).Nucleic Acids Res., 32, 1018-27.

28. Structure-function relationship in serine hydroxymethyltransferase.Appaji Rao N, Ambili M, Jala VR, Subramanya, H.S. and Savithri HS (2003).Biochim Biophys Acta., 1647, 24-9.

29. Different unfolding pathways for mesophilic and thermophilic homologues of serine hydroxymethyltransferase.Bhatt AN, Prakash K, Subramanya H.S. and Bhakuni V. (2002).Biochemistry, 41, 12115-23.

30. Crystal Structure of Binary and Ternary Complexes of Serine Hydroxymethyl- transferase from B.stearothermophilus: Insights into the Catalytic Mechanism. Trivedi, V., Gupta, A., Rao, J.V.K., Saravanan, P., Rao, G.S.J., Rao, A.N., Savithri,H.S. and Subramanya, H.S. (2002).J. Biol. Chem, 277, 17161-69.

31. Purification and Crystallization of CII: An unstable Transcription Activator from Phage lambda.Datta B., Chakrabarti, P., Subramanya, H.S., and Parrack, P. (2001).Biochem. Biophys. Res. Commun. 288, 997-1000.

32. Crystal Structure of Rv2118c: An AdoMet-dependent Methyltransferase from Mycobacterium tuberculosis H37Rv. Gupta, A., Hari Kumar, P., Dineshkumar, T.K., Varshney, U. and Subramanya, H.S.(2001).J. Mol. Biol. 312, 381-391.
33. Dysobinin, a tetranortriterpenoid. Sarkhel S, Jain GK, Singh S, Subramanya, H.S., Maulik PR. (2000). Acta Crystallogr C., 56, E253-4.

34. Three-Dimensional quantitative structural activity relationship (3D-QSAR) studies of some 1,5-Diarylpyrazoles: Analogue based design of selective Cyclooxygenase-2 Inhibitors. Desiraju, G.R., Gopalakrishnan, B., Jetti, R.K.R., Raveendra, D., Sarma, J.A.R.P. and Subramanya, H.S. (2000). Molecules, 5, 945-955.

35. Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism. Velankar, S.S., Soultanas, P., Dillingham, M.S., Subramanya, H.S. and Wigley, D.B. (1999).Cell, Vol. 97, 75-84.

36. Characterization of Bacillus stearothermophylus PcrA helicase: Evidence against an active rolling model.Bird, L.E., Brannigan, J.A., Subramanya, H.S. and Wigley, D.B. (1998).Nucl. Acids Res. 26, 2686-2693.

37. Helicases: A unifying structural theme? Bird, L.E., Subramanya, H.S. and Wigley, D.B. (1998).Curr. Opin. Struc. Biol., 8, 14-18.

38. Crystal structure of the site specific recombinase XerD. Subramanya, H.S., Arciszewska, L.K., Baker, R., Bird, L.E., Sherrat, D.J. and Wigley, D.B. (1997). EMBO J., 16, 5178-5187.

39. Structure of sesbania mosaic viruses at 3 Å resolution. Murthy, M.R.N., Bhuvaneswari, M., Subramanya, H.S., Gopinath, K., Savithri, H.S. (1997) Biophys. Chem., Vol. 68, 33-42.

40. Architecture of small RNA viruses. Bhuvaneswari, M., Subramanya, H.S., Murthy, M.R.N., Gopinath, K. and Savithri, H.S. (1997). Prog. Crystal Growth and Charact., Vol. 34, 1-10.

41. Crystallization and preliminary crystallographic analysis of the DNA gyrase B protein from B. stearothermophilus. Tsai, F.T.F., Subramanya, H.S., Brannigan, J.A. and Wigley, D.B. (1996). Acta Cryst., 1216-1218.

42. Crystal structure of a Dexx box DNA helicase. Subramanya, H.S., Bird, L.E., Brannigan, J.A. and Wigley, D.B. (1996). Nature, 384, 379-383.

43. Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7. Subramanya, H.S., Doherty, A.J., Ashford, S.R. and Wigley, D.B. (1996). Cell, 85, No.4, 607-615.

44. Bacteriophage T7 DNA ligase: Overexpression, purification, crystallization and characterization. Doherty, A.J., Ashford, S.R., Subramanya, H.S. and Wigley, D.B. (1996). J. Biol. Chem, 271, 11083-11089.

45. Preliminary crystallographic analysis of the ParE subunit of E.coli topoisomerase IV. Subramanya, H.S., Peng, H., Marians, K.J. and wigley, D.B. (1996). Acta Cryst., D52, 579-580.

46. Enzymatic ketonization of 2-hydroxymuconate: Specificity and mechanism investigated by the crystal structure of two isomerases. Subramanya, H.S., Roper, D.I., Dauter, Z., Dodson, E.J., Davis, G.J., Wilson, K.S. and Wigley, D.B. (1996). Biochemistry, 35, 792-802.

47. Structure of sesbania mosaic virus at 3 Å resolution. Bhuvaneswari, M., Subramanya, H.S., Gopinath, K., Savithri, H.S., Nayudu, M.V. and Murthy, M.R.N. (1995). Structure, Vol. 3, No. 10, 1021-1030.

48. Structure of sesbania mosaic virus at 4.7 Å resolution. Subramanya, H.S. (1995) J. Indian Inst. Sci., 75, 720-722

49. Preliminary crystallographic analysis of 4-oxalocrotonate tautomerase reveals the oligomeric structure of the enzyme. Roper, D.I., Subramanya, H.S., Shingler, V. and Wigley, D.B. (1994). J. Mol. Biol. 243, 799-801

50. Structure of sesbania mosaic virus at 4.7 Å resolution and partial sequence of the coat protein. Subramanya, H.S., Gopinath, K., Nayudu, M.V., Savithri, H.S. and Murthy, M.R.N. (1993) J.Mol.Biol 229, 20-25.

Patents 

1. Azine Compounds as Glucokinase Activators (2009)
   SE Badiger, KF Fosgerau, N Vrang, VD Chaudhari, JJ Naik, J Auxcilia, RR Reddy, HS Subramanya, PV Reddy, BNS Reddy,
   WO2009/083553A1
2. Hetereocyclic Compounds as MEK Inhibitors (2010)
   D Chikkanna, C McCarthy, H Moebitz, C Pandit, R Sistla, H Subramanya
   WO/2010/121646
3. Piperazine derivatives as inhibitors of stearoyl-CoA desaturase (2011)
   K Sundaresan, SN Raikar, SR Sammeta, G Prabhu, H Subramanya, A Bischoff
   US Patent 8,039,463
4. Piperidine derivatives as inhibitors of stearoyl-CoA desaturase (2012)
   K Sundaresan, PBK Rao, B Ainan, H Ayyamperumal, AR Girish, S Tatiparthy, G Prabhu, H Subramanya, A Bischoff
   US Patent 8,129,376
5. Substituted quinazoline and pyrido-pyrimidine derivatives (2012)
   RA Smith, SK Thompson, S Hosahalli, M Bejugam, S Nanduri, P Sunil Kumar, M Natarajan
   WO/2012/058671
6. Isoxazolines as therapeutic agents (2012)
   DJ Calderwood, EC Breinlinger, SL Swann, VS Chitty, S Hosahalli
   WO/2012/151158
7. Substituted pyridine derivatives as FABI inhibitors (2013)
   M Takhi, S Hosahalli, SK Panigrahi, MK Mahadari, CR Kottam, N Abd Rahman, R Yusof
   WO/2013/080222
8. Bicyclic Heterocycles as IRAK4 Inhibitors (2013) A Boruah, HS Subramanya, S Mukherjee WO/2013/042137
9. Trisubstituted Benzotriazole Derivatives as Dihydroorotate Oxygenase Inhibitors (2014)
   SSR Thunuguntla, S Hosahalli, SR Kunnam
   WO/2014/128669
10. Tetrahydropyridine derivatives as FabI inhibitors (2015) M Takhi, S Hosahalli, SK Panigrahi
    WO/2014/195844
11. Dihydroorotate Dehydrogenase Inhibitors (2015)
    SSR Thunuguntla, H Subramanya, SR Kunnam, SRS Vijay, C Bingi, R Kusanur, M Schwarz, M Arlt
    US9006454B2
12. Bicyclic heterocycle derivatives as bromodomain inhibitors (2015) S Samajdar, C Abbineni, S Sasmal, S Hosahalli
    WO2015104653A1
13. Substituted amino-pyrimidine derivatives (2015)
    RA Smith, A Venkatesan, M Bejugam, S Hosahalli, S Nanduri
    US 9145411B2
14. 3-(pyrazolyl)-1H-pyrrolo [2, 3-b] pyridine derivatives as kinase inhibitors (2016) VR Gummadi, S Hosahalli, S Nanduri, GA Renukappa
    US Patent 9,353,107
15. Crystalline Structure of FABI from Burkholderia Pseudomallei (2017) NR Krishnamurthy, A Lakshminarasimhan, T Antony, HS Subramanya
    US20170088822A1
16. Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/mTOR pathways
    SK Thompson, RA Smith, S Reddy, TM John, VK Nyavanandi, S Hosahalli, V Potluri, SK Panigrahi, PR Nadipalli, S Sengupta (2019)
    US Patent 10,226,468
17. Pyrimido-pyridazinone compounds and methods of use thereof (2019)
    A Venkatesan, RA Smith, H Subramanya, V Potluri, SK Panigrahi, V Basetti, K Kunta
    US Patent 10,183,944
18. 1, 4, 6-trisubstituted-2-alkyl-1H-benzo [d] imidazole derivatives as dihydroorotate oxygenase inhibitors (2020)
    SSR Thunuguntla, S Hosahalli, SK Panigrahi, M Schwarz, M Arlt (2020)
    WO2018154088A1
19. Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors (2021)
    K Nellore, S Hosahalli WO2018197997A1

Bridging Science and Art: A Lecture That Transcended Boundaries

April 3, 2025

The university auditorium witnessed an extraordinary lecture by Prof. Ashok Vudayagiri from the School of Physics, University of Hyderabad, titled “Bridging Science and Art: From Mundane to Profound.” The event, a mesmerizing blend of poetry, mathematics, architecture, and astronomy, left the audience in awe of the hidden connections between seemingly disparate disciplines. Prof. Vudayagiri began

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Sammilana – The Joy of Togetherness – 2nd Edition

April 3, 2025

The 2nd edition of Sammilana at Chanakya University was a celebration of unity, appreciation, and cultural harmony. This compassionate gathering, deeply rooted in Bharatiya ethos, recognized and rewarded the outstanding achievements of students, faculty, and staff with certificates of appreciation. It was a moment of collective pride as we honoured the excellence across various domains

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Bangalore on Changing landscape of Corporate and Commercial Law in India Special Talk by Advocate S. S. Naganand

March 29, 2025

A special talk was delivered by Advocate S. S. Naganand – Senior Partner, Just Law Advocates, Bangalore, on ‘Changing landscape of Corporate and Commercial Law in India’. The event was attended by students and faculty, gaining an insight into the changing legal landscape that regulates corporations and businesses in India. Sri S. S. Naganand discussed

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